Product and Process Engineering - Delft University of Technology

Josette Moret

Josette Moret

Contact details

  • Josette Moret
  • Delft University of Technology
  • Dept. Chemical Engineering - PPE
  • Room F2.480
  • van der Maasweg, 9, 2629 HZ, Delft, The Netherlands

Research interests and expertises

  • Atomic layer deposition
  • Radiation science
  • elemental anlysis
  • adsorption/desorption


  • MSc Chemical Engineering, Delft University of Technology, 2013
  • BSc, Chemical Engineering, Delft University of Technology, 2011


Research description

Development of a 177Lu generator based on the long lived 177mLu:

177Lu is used as a radio therapeutic in Peptide Receptor Radionuclide Therapy (PRRT). Currently, the 177Lu is produced either via irradiation of 176Lu or 176Yb with neutrons. Because of the 6.7 days half life of 177Lu treatment facilities must be weekly supplied with radioactive lutetium in order to maintain normal operation. A generator based on the long lived 177mLu could decrease the dependency on nuclear reactors and increase the shipping distance from the currently available distribution locations.

Aim: Develop a generator which gives ultra-high specific activity 177Lu by finding physical proof for bond rupture to happen with 177mLu/177Lu, study multiple carries, including chelators, determine elution efficiencies of 177Lu etc.

Student projects

If you are interested in the topic, please contact me at, to discuss the possibilities.

. © Delft University of Technology - PPE group 2015