Transport Phenomena - Delft University of Technology

Saeid Khalafvand

Saeid Khalafvand (photo)

Heart Failure and 4D Flow: Computational Fluid Dynamics of the Blood Flow within Pulsating Heart

Contact details

  • Saeid Khalafvand
  • Delft University of Technology
  • Faculty of Applied Sciences (TNW)
  • Department of Chemical Engineering
  • Transport Phenomena Group
  • Building 58, Room F2.110
  • van der Maasweg 9, Delft, The Netherlands

Research interests

  • Computational Fluid Dynamics
  • Biofluids and Biomechanics
  • Multi-physics problems (i.e. Fluid-Structure Interaction)
Moving Heart animation

Personal education

I am a computational and mathematical modeler who is specialized in solving problems in biomedical and mechanical engineering to help make lives better.

  • Post-Doctoral Reaserch Fellow, University of Texas, Department of Mechanical Engineering, Cardiovascular Biomechanics Lab, Texas, USA
  • PhD, Nanyang Technological University, School of Mechanical and Aerospace Engineering, Singapore
              University of Pittsburgh, Depatrtment of Bioengineering, PA, USA
  • MSc, Isfahan University of Technology, Department of Mechanical Engineering, Isfahan, Iran

Research description

My current research is focused on the CFD analysis of blood flow in human heart. We will combine CFD with experimental data and physical models to determine pressure-volume loops to improve diagnosis and follow effect of therapy on heart failure. The CFD will focus on solving the Navier-Stokes equations on a moving mesh, using experimental data as boundary conditions. The MRI experimental data will be used in defining the dynamical (spatial and temporal) variation of the ventricle geometry. The US measurements will be used to provide more detailed insights into regions in the proximity of valves, i.e. they will be used to specify the temporal evolutions of the three-dimensional in/out jets. In addition, the MRI measured velocity field will be used for validation of the CFD simulations. The project will be closely executed in cooperation with our colleagues from Leiden University Medical Center and Erasmus Medical Center Rotterdam where MRI and US measurements will be performed.

Student projects

Currently, there is some student projects related to modelling of blood flow in human left ventricle and arteries. Please refer to (MSc/BSc Projects, pages 41-43) for the details and descriptions or directly contact to me.


Last modified: June 22 2016. © Delft University of Technology - TP group 2012